A recently published independent studies, Kanchwala (et. al.) , comparing Radiesse and three other soft-tissue fillers for facial-volume augmentation recommended Radiesse as the preferred filler for augmenting nasolabial folds. The longevity of Radiesse was rated as excellent, averaging 11 months. On the other hand, Restylane and Hylaform lasted only 4.5 months and 3 months respectively. In addition, investigators concluded that Radiesse is a cost-effective option in treating nasolabial folds due to its overall longevity. Published independent studies show that a typical treatment for nasolabial folds lasts approximately one year to 18 months, with an occasional touchup recommended.