A Nacogdoches house was destroyed by a fire this evening. The call came in to 911 operators at 9:47 from a neighbor who spotted the flames. The house, located on Cottonwood Street had two people and four dogs in the house at the time of the fire. They all made it out without injuries. Firefighters said the cause of the fire is still under investigation. Stay tuned to KTRE for any new information.